Factors Regulating Stem Cell Biology in Development and Disease.
نویسندگان
چکیده
1 Institute of Neuroanatomy & Developmental Biology, Eberhard Karls University Tübingen, 72074 Tübingen, Germany 2Center for Neurosensory Systems (ZFN), Eberhard Karls University Tübingen, 72074 Tübingen, Germany 3Children’s Hospital of Philadelphia (CHOP), University of Pennsylvania, 3501 Civic Center Boulevard, Philadelphia, PA 19104, USA 4Division of Experimental Hematology & Cancer Biology, 3333 Burnet Avenue, Cincinnati, OH 45229, USA 5II. Medizinische Klinik und Poliklinik, Klinikum rechts der IsarMünchen, Technische Universität München, 81675Munich, Germany 6Department of Internal Medicine I, University of Ulm, Albert-Einstein-Allee 11, 89081 Ulm, Germany
منابع مشابه
Comparison of BAX and Bcl-2 Expression During Human Embryonic Stem Cell Differentiation into Cardiomyocytes and Doxorubicin-induced Apoptosis
Back ground: Although the cell differentiation is an inseparable part of development in multicellular organisms, the regulating molecular pathway of it still is not fully defined. In the other hand, apoptosis is a fundamental physiological process which plays an essential role in a variety of biological events during development. Moreover, recent studies have found that apoptosis shows several ...
متن کاملStem Cells Application in Modeling of Human Genetic Diseases
The use of animal models in modeling of human genetic disease has many advantages. In some cases, however, this method may not be applicable due to some limitations, such as differences in tissue composition, anatomy and physiology of humans and animals. Isogenic human disease models are a population of cells that are selected or engineered to model a specific genetic disease, in vitro. They ar...
متن کاملHuman activated macrophages and hypoxia: a comprehensive review of the literature
Macrophages accumulate in poorly vascularised and hypoxic sites including solid tumours, wounds and sites of infection and inflammation where they can be exposed to low levels of oxygen for long periods. Up to date, different studies have shown that a number of transcription factors are activated by hypoxia which in turn activate a broad array of mitogenic, pro-invasive, pro-angiogenic, and pro...
متن کاملApplication of extracellular vesicles in the treatment of inflammatory bowel disease
Introduction: Inflammatory bowel disease(IBD) is caused by genetic, environmental, microbial and immune factors. IBD has two primary forms: Ulcerative colitis and Crohn´s disease. The incidence of IBD has significantly increased over the last few decades. Given that patients have poor response to drug treatments or are resistant to drug therapies, new therapies are needed for gastrointestinal i...
متن کاملNovel Cell-Based Therapies in Hepatic Disorders
In the recent decade, liver diseases with high mortality rate have became one of the major health problems worldwide. Liver transplantation is the most effective and the standard treatment for decompensated liver disease, but, shortage of available organs and inaccuracy in modeling of the liver diseases are the most limiting issues in treatment. Regenerative medicine and cell based therapy str...
متن کاملEffect of Dexamethasone, Insulin and EGF on the Myogenic Potential on Human Endometrial Stem Cell
Human endometrium contains mesenchymal stem cells (eMSC) which have the ability to differentiate into three cell lineages and the potential in therapeutic applications. We hypothesize that using environmental induction in culture media such as dexamethasone, human recombinant insulin and human epidermal growth factor (hEGF) can differentiate endometrial stem cells into myoblast. These agents ha...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Stem cells international
دوره 2016 شماره
صفحات -
تاریخ انتشار 2016